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Pilonidal disease is a chronic skin infection in the crease of the buttocks, marked by cysts in this area. A pilonidal cyst is a round sac of tissue filled with air or fluid that often looks like a pimple at the bottom of your tailbone. Pilonidal cysts are thought to be caused by infected hair follicles in this area.
Your doctor may need to open and drain the cyst, or you may need surgery to remove the cyst altogether for recurring infections.